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KMID : 0043320010240050427
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Archives of Pharmacal Research
2001 Volume.24 No. 5 p.427 ~ p.430
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Antioxidative Components from the Aerial Parts of Lactuca scariola L.
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Kim Dae-Keun
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Abstract
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The antioxidant activity of Lactuca scariola (Compositae) was investigated by measuring the radical scavenging effect on DPPH (1,1-diphenyl-2-picrylhydrazyl) radical. The methanolic extract of the aerial parts of Lactuca scariola showed strong radical scavenging activity. The EtOAc soluble fraction exhibited a stronger activity than the others, and was purified by silica gel and Sephadex LH-20 column chromatography. Quercetin-3-O--D-glucopyranoside, luteolin-7-O--D-glucopyranoside, luteolin, quercetin and kaempferol, together with 11,13-dihydrolactucin were isolated from the EtOAc soluble fraction as active ingredients.
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KEYWORD
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Lactuca scarioia, Compositae, Antioxidant activity, Flavonoids
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